The Best Western Premier Hotel Santo Domingo is situated in a building that dates back some 400 years and is located in a quiet square in the center of Madrid, approximately seven miles from Madrid Airport. This location is also close to Puerta del Sol, the Royal Palace, Plaza Mayor, Teatro Real, and the main shopping areas.

Hotel amenities include the dining room, room service, laundry facilities, and safety deposit.

All rooms feature cable TV, dataports, clock radios, hairdryers, coffee/tea makers, and additional in-room toiletries.