Melia Barcelona is a block away from the junction of Avinguda Sarria and Avinguda Diagonal and approximately six miles from Barcelona International Airport. Within three miles of the hotel are Sagrada Familia, Olympic Port, Barrio Gotico, and Imax Aquarium. The hotel is 20 miles from Ramblas, 22 miles from Montserrat, and 38 miles from Costa Brava. Parking is available.

Hotel amenities include the on-site restaurant serving both Catalan and international dishes, as well as a large brunch. The cocktail bar, Drinking in the Rain, provides drinks and piano music six nights a week. There is also a coffee shop in the hotel. Room service is available 24 hours a day. The hotel also has a lobby waterfall, fitness center, sauna, solarium, gift shop, and more.

All rooms feature satellite TV, minibars, bathroom telephones, and hairdryers.