Aldrovandi Palace is adjacent to the 17th-century Borghese Gardens and approximately 20 miles from Fiumicino International Airport. This location is also a quarter-mile from Borghese Gallery, half a mile from the National Gallery of Modern Art, one mile from the Spanish Steps, and two miles from the Piazza della Repubblica, Trevi Fountain, Stazione Termini Train Station, Piazza Venezia, and Colosseum.

Hotel amenities include the fitness room, swimming pool, poolside restaurant, garden dining, and 24-hour room service. The hotel also offers private parking, free weekday newspapers, turndown service, valet laundry service, and complimentary hourly shuttle buses to and from Rome's shopping district.

All rooms feature air-conditioning, interactive TVs, voicemail, dataports, safes, desks, bathrobes and slippers, free weekday newspapers, free umbrellas, hairdryers, and minibars.