Set on six acres in the Cotswolds, Thistle Cheltenham is three miles from the center of the Georgian spa town of Cheltenham and approximately 44 miles from Bristol Airport. This location is also one mile from Cheltenham Spa Train Station, three miles from the Pittville Pump Rooms and Cheltenham Race Course, six miles from Gloucester, and 45 miles from Bath.

Hotel amenities include the health club, sauna, steam room, indoor pool, Burford Restaurant (international dishes), and Co Motion (snacks and light refreshments). The hotel also offers room service, parking, laundry facilities, and a concierge.

All rooms feature dataports, tea/coffee facilities, trouser presses, hairdryers, and satellite TV.